Protein Targeting, Transport, and TranslocationRoss Dalbey, Gunnar von Heijne Elsevier, 09/04/2002 - 336 من الصفحات Protein Targeting, Transport, and Translocation presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields.
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النتائج 1-5 من 36
الصفحة 48
... SecYEG DF YajC L C N N C ATP N Figure 4.1 Schematic overview of the components of bacterial translocase.A protein with a signal sequence emerging from the ribosome can be targeted to the translocase by at least three different routes ...
... SecYEG DF YajC L C N N C ATP N Figure 4.1 Schematic overview of the components of bacterial translocase.A protein with a signal sequence emerging from the ribosome can be targeted to the translocase by at least three different routes ...
الصفحة 52
... regions simultaneously occupy multiple binding sites on the tetrameric SecB to allow a high affinity of interaction (Kd 5–50 nM). The three-dimensional structure of 3! 1 2 4 5! GTP GTP PGDP SecYEG PGDP. 52. Protein export in bacteria.
... regions simultaneously occupy multiple binding sites on the tetrameric SecB to allow a high affinity of interaction (Kd 5–50 nM). The three-dimensional structure of 3! 1 2 4 5! GTP GTP PGDP SecYEG PGDP. 52. Protein export in bacteria.
الصفحة 53
... SecYEG PGDP Figure 4.2 Schematic overview of SRP-mediated co-translational targeting of nascent preproteins to the ... SecYEG complex. The large ribosomal subunit also binds directly to the SecYEG complex via the 23S rRNA. (4) Subsequent ...
... SecYEG PGDP Figure 4.2 Schematic overview of SRP-mediated co-translational targeting of nascent preproteins to the ... SecYEG complex. The large ribosomal subunit also binds directly to the SecYEG complex via the 23S rRNA. (4) Subsequent ...
الصفحة 54
... SecYEG channel. A negatively charged solventexposed surface on each of the sides of the SecB tetramer (Xu et al., 2000) electrostatically associates with the positively charged carboxyl-termini of the SecA dimer (Fekkes et al., 1997) ...
... SecYEG channel. A negatively charged solventexposed surface on each of the sides of the SecB tetramer (Xu et al., 2000) electrostatically associates with the positively charged carboxyl-termini of the SecA dimer (Fekkes et al., 1997) ...
الصفحة 55
... SecYEG-bound SecA where SecB binds with a high affinity binding to a carboxyl-terminal zinc-binding domain of SecA ... SecYEG N 3 5! N 3! termed the SecYEG complex and a unit that directs the. C C N N N C Periplasm N N N Translocase, a ...
... SecYEG-bound SecA where SecB binds with a high affinity binding to a carboxyl-terminal zinc-binding domain of SecA ... SecYEG N 3 5! N 3! termed the SecYEG complex and a unit that directs the. C C N N N C Periplasm N N N Translocase, a ...
المحتوى
35 | |
47 | |
74 | |
Chapter 6 Membrane Protein Insertion into Bacterial Membranes and the Endoplasmic Reticulum | 107 |
Chapter 7 Disulfide Bond Formation in Prokaryotes and Eukaryotes | 131 |
Chapter 8 The Unfolded Protein Response | 151 |
The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection | 180 |
Chapter 10 Translocation of Proteins into Mitochondria | 214 |
Chapter 12 Import of Proteins into Peroxisomes | 268 |
Chapter 13 Nucleocytoplasmic Transport | 293 |
Chapter 14 Protein Transport to the Yeast Vacuole | 322 |
Chapter 15 The Secretory Pathway | 358 |
Chapter 16 Vesicular Transport | 377 |
Chapter 17 ConclusionPerspective | 402 |
Index | 407 |
Chapter 11 The Import and Sorting of Protein into Chloroplasts | 240 |
طبعات أخرى - عرض جميع المقتطفات
عبارات ومصطلحات مألوفة
Acad Sci USA activity amino acid bacterial bilayer binding Biochem biogenesis Biol Chem Blobel brane cargo Cell Biol chaperones chloroplast cisternae clathrin co-translational compartment complex components cytoplasmic cytosolic degradation disulfide bond domain DsbA DsbC EMBO encoded endoplasmic reticulum endosome enzymes Escherichia coli eukaryotic export folding function fusion genes Golgi Görlich homolog hydrophobic importin inner membrane insertion interaction involved Ire1p isomerase kinase lipid lumen machinery matrix mediated membrane proteins misfolded mitochondrial molecular molecules mRNA mutants N-terminal nascent chain Natl Acad Sci nuclear organelle outer membrane peptidase periplasmic peroxisomal peroxisomal membrane Pex5p plasma membrane polypeptide pore precursor preprotein presequence Proc Natl Acad protease proteasome protein import protein translocation receptor residues ribosome role SecA SecB secretory pathway secretory proteins SecYEG signal peptide signal sequence structure substrate subunit synthesized teins thylakoid translocase translocon transmembrane transport unfolded proteins vacuolar vacuole vesicles vitro yeast
مقاطع مشهورة
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الصفحة 399 - R. (1980). Identification of 23 complementation groups required for posttranslational events in the yeast secretory pathway. Cell 21, 205-215.
الصفحة 319 - Robbins, J., Dilworth, SM, Laskey, RA, and Dingwall, C. (1991). Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence. Cell 64, 615-623.
الصفحة 399 - BS, and Rothman, JE (1986). A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell, 46, 171-184.
الصفحة 32 - J., 1972. Mechanism of assembly of the outer membrane of Salmonella typhimurium: Isolation and characterization of cytoplasmic and outer membrane, J.
الصفحة 238 - Schatz, G., and Dobberstein, B. (1996). Common principles of protein translocation across membranes.
الصفحة 44 - Berks, BC (1996) A common export pathway for proteins binding complex redox cofactors? Mol Microbiol 22: 393-404. Berks, BC, Sargent, F. and Palmer, T. (2000) The Tat protein export pathway. Mol Microbiol 35: 260-274.