Protein Targeting, Transport, and TranslocationRoss Dalbey, Gunnar von Heijne Elsevier, 09/04/2002 - 336 من الصفحات Protein Targeting, Transport, and Translocation presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields.
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من داخل الكتاب
النتائج 1-5 من 44
الصفحة 28
... amino acid sequence) is fused to the protein of interest. Typically, the addition of the tag does not affect the structure/function of the protein. Immunofluorescence is then used to determine the protein's location by adding antibodies ...
... amino acid sequence) is fused to the protein of interest. Typically, the addition of the tag does not affect the structure/function of the protein. Immunofluorescence is then used to determine the protein's location by adding antibodies ...
الصفحة 35
... amino acid sequence at Protein Targeting, Transport & Translocation ISBN 0-12-200731-X Copyright 2002, Elsevier Science Ltd. All rights of reproduction in any form reserved the N-terminus of a precursor protein would be a simple Chapter ...
... amino acid sequence at Protein Targeting, Transport & Translocation ISBN 0-12-200731-X Copyright 2002, Elsevier Science Ltd. All rights of reproduction in any form reserved the N-terminus of a precursor protein would be a simple Chapter ...
الصفحة 41
... amino acids N-terminal 'transit peptides' target proteins to the chloroplast import machinery and ensure translocation across the two envelope membranes into the stroma. They have a distinct amino acid composition, with few acidic but ...
... amino acids N-terminal 'transit peptides' target proteins to the chloroplast import machinery and ensure translocation across the two envelope membranes into the stroma. They have a distinct amino acid composition, with few acidic but ...
الصفحة 42
... amino acid sequences, (ii) to search the mature parts of the protein for features known to correlate with the subcellular localization (overall amino acid composition, preponderance of glycosylation sites, etc.), and (iii) to look for ...
... amino acid sequences, (ii) to search the mature parts of the protein for features known to correlate with the subcellular localization (overall amino acid composition, preponderance of glycosylation sites, etc.), and (iii) to look for ...
الصفحة 43
... amino acid composition from other proteins, this can be used as a basis for the prediction. The best-known method based on this idea is PSORT (Nakai and Horton, 1999), although a couple of other similar methods have been presented ...
... amino acid composition from other proteins, this can be used as a basis for the prediction. The best-known method based on this idea is PSORT (Nakai and Horton, 1999), although a couple of other similar methods have been presented ...
المحتوى
35 | |
47 | |
74 | |
Chapter 6 Membrane Protein Insertion into Bacterial Membranes and the Endoplasmic Reticulum | 107 |
Chapter 7 Disulfide Bond Formation in Prokaryotes and Eukaryotes | 131 |
Chapter 8 The Unfolded Protein Response | 151 |
The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection | 180 |
Chapter 10 Translocation of Proteins into Mitochondria | 214 |
Chapter 12 Import of Proteins into Peroxisomes | 268 |
Chapter 13 Nucleocytoplasmic Transport | 293 |
Chapter 14 Protein Transport to the Yeast Vacuole | 322 |
Chapter 15 The Secretory Pathway | 358 |
Chapter 16 Vesicular Transport | 377 |
Chapter 17 ConclusionPerspective | 402 |
Index | 407 |
Chapter 11 The Import and Sorting of Protein into Chloroplasts | 240 |
طبعات أخرى - عرض جميع المقتطفات
عبارات ومصطلحات مألوفة
Acad Sci USA activity amino acid bacterial bilayer binding Biochem biogenesis Biol Chem Blobel brane cargo Cell Biol chaperones chloroplast cisternae clathrin co-translational compartment complex components cytoplasmic cytosolic degradation disulfide bond domain DsbA DsbC EMBO encoded endoplasmic reticulum endosome enzymes Escherichia coli eukaryotic export folding function fusion genes Golgi Görlich homolog hydrophobic importin inner membrane insertion interaction involved Ire1p isomerase kinase lipid lumen machinery matrix mediated membrane proteins misfolded mitochondrial molecular molecules mRNA mutants N-terminal nascent chain Natl Acad Sci nuclear organelle outer membrane peptidase periplasmic peroxisomal peroxisomal membrane Pex5p plasma membrane polypeptide pore precursor preprotein presequence Proc Natl Acad protease proteasome protein import protein translocation receptor residues ribosome role SecA SecB secretory pathway secretory proteins SecYEG signal peptide signal sequence structure substrate subunit synthesized teins thylakoid translocase translocon transmembrane transport unfolded proteins vacuolar vacuole vesicles vitro yeast
مقاطع مشهورة
الصفحة 46 - Biochem 133: 17-21. von Heijne, G. (1986) A new method for predicting signal sequence cleavage sites. Nucleic Acids Res 14: 4683-4690.
الصفحة 399 - R. (1980). Identification of 23 complementation groups required for posttranslational events in the yeast secretory pathway. Cell 21, 205-215.
الصفحة 319 - Robbins, J., Dilworth, SM, Laskey, RA, and Dingwall, C. (1991). Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence. Cell 64, 615-623.
الصفحة 399 - BS, and Rothman, JE (1986). A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell, 46, 171-184.
الصفحة 32 - J., 1972. Mechanism of assembly of the outer membrane of Salmonella typhimurium: Isolation and characterization of cytoplasmic and outer membrane, J.
الصفحة 238 - Schatz, G., and Dobberstein, B. (1996). Common principles of protein translocation across membranes.
الصفحة 44 - Berks, BC (1996) A common export pathway for proteins binding complex redox cofactors? Mol Microbiol 22: 393-404. Berks, BC, Sargent, F. and Palmer, T. (2000) The Tat protein export pathway. Mol Microbiol 35: 260-274.