Protein Targeting, Transport, and TranslocationRoss Dalbey, Gunnar von Heijne Elsevier, 09/04/2002 - 336 من الصفحات Protein Targeting, Transport, and Translocation presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields.
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من داخل الكتاب
النتائج 1-5 من 43
الصفحة xi
... mRNAs for secretory proteins are translated on ER-bound ribosomes and not on free ribosomes. It emphasized the idea that all ... mRNA for the light chain of IgG was translated in a membrane-free translation system. However, it Foreword.
... mRNAs for secretory proteins are translated on ER-bound ribosomes and not on free ribosomes. It emphasized the idea that all ... mRNA for the light chain of IgG was translated in a membrane-free translation system. However, it Foreword.
الصفحة xiii
... mRNA of the vesicular stomatitis virus (VSV) membrane glycoprotein (G) was translated in the coupled translation–translocation system. These experiments were paradigmatic as they showed that the asymmetric integration of a membrane ...
... mRNA of the vesicular stomatitis virus (VSV) membrane glycoprotein (G) was translated in the coupled translation–translocation system. These experiments were paradigmatic as they showed that the asymmetric integration of a membrane ...
الصفحة 19
... mRNA that lack a stop codon. After salt stripping, followed by centrifugation through a high salt sucrose cushion to remove the cytosol, membranes can be added as well as cytosol or purified proteins. The targeting of the ribosome ...
... mRNA that lack a stop codon. After salt stripping, followed by centrifugation through a high salt sucrose cushion to remove the cytosol, membranes can be added as well as cytosol or purified proteins. The targeting of the ribosome ...
الصفحة 21
... mRNA technology (Gilmore et al., 1991) (Figure 2.6). Due to the absence of a stop codon in the truncated Promoter Gene of interest Stop Plasmid DNA Restriction site DNA fragment In vitro transcription Truncated mRNA In vitro translation ...
... mRNA technology (Gilmore et al., 1991) (Figure 2.6). Due to the absence of a stop codon in the truncated Promoter Gene of interest Stop Plasmid DNA Restriction site DNA fragment In vitro transcription Truncated mRNA In vitro translation ...
الصفحة 22
... mRNA technology, in which the site-specific photocrosslinking approach is used, is to introduce an amber codon within the nascent polypeptide and then use an amber suppressor tRNA that is charged with a photoactivatable probe. The ...
... mRNA technology, in which the site-specific photocrosslinking approach is used, is to introduce an amber codon within the nascent polypeptide and then use an amber suppressor tRNA that is charged with a photoactivatable probe. The ...
المحتوى
35 | |
47 | |
74 | |
Chapter 6 Membrane Protein Insertion into Bacterial Membranes and the Endoplasmic Reticulum | 107 |
Chapter 7 Disulfide Bond Formation in Prokaryotes and Eukaryotes | 131 |
Chapter 8 The Unfolded Protein Response | 151 |
The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection | 180 |
Chapter 10 Translocation of Proteins into Mitochondria | 214 |
Chapter 12 Import of Proteins into Peroxisomes | 268 |
Chapter 13 Nucleocytoplasmic Transport | 293 |
Chapter 14 Protein Transport to the Yeast Vacuole | 322 |
Chapter 15 The Secretory Pathway | 358 |
Chapter 16 Vesicular Transport | 377 |
Chapter 17 ConclusionPerspective | 402 |
Index | 407 |
Chapter 11 The Import and Sorting of Protein into Chloroplasts | 240 |
طبعات أخرى - عرض جميع المقتطفات
عبارات ومصطلحات مألوفة
Acad Sci USA activity amino acid bacterial bilayer binding Biochem biogenesis Biol Chem Blobel brane cargo Cell Biol chaperones chloroplast cisternae clathrin co-translational compartment complex components cytoplasmic cytosolic degradation disulfide bond domain DsbA DsbC EMBO encoded endoplasmic reticulum endosome enzymes Escherichia coli eukaryotic export folding function fusion genes Golgi Görlich homolog hydrophobic importin inner membrane insertion interaction involved Ire1p isomerase kinase lipid lumen machinery matrix mediated membrane proteins misfolded mitochondrial molecular molecules mRNA mutants N-terminal nascent chain Natl Acad Sci nuclear organelle outer membrane peptidase periplasmic peroxisomal peroxisomal membrane Pex5p plasma membrane polypeptide pore precursor preprotein presequence Proc Natl Acad protease proteasome protein import protein translocation receptor residues ribosome role SecA SecB secretory pathway secretory proteins SecYEG signal peptide signal sequence structure substrate subunit synthesized teins thylakoid translocase translocon transmembrane transport unfolded proteins vacuolar vacuole vesicles vitro yeast
مقاطع مشهورة
الصفحة 46 - Biochem 133: 17-21. von Heijne, G. (1986) A new method for predicting signal sequence cleavage sites. Nucleic Acids Res 14: 4683-4690.
الصفحة 399 - R. (1980). Identification of 23 complementation groups required for posttranslational events in the yeast secretory pathway. Cell 21, 205-215.
الصفحة 319 - Robbins, J., Dilworth, SM, Laskey, RA, and Dingwall, C. (1991). Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence. Cell 64, 615-623.
الصفحة 399 - BS, and Rothman, JE (1986). A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell, 46, 171-184.
الصفحة 32 - J., 1972. Mechanism of assembly of the outer membrane of Salmonella typhimurium: Isolation and characterization of cytoplasmic and outer membrane, J.
الصفحة 238 - Schatz, G., and Dobberstein, B. (1996). Common principles of protein translocation across membranes.
الصفحة 44 - Berks, BC (1996) A common export pathway for proteins binding complex redox cofactors? Mol Microbiol 22: 393-404. Berks, BC, Sargent, F. and Palmer, T. (2000) The Tat protein export pathway. Mol Microbiol 35: 260-274.